antibody

Granulin Antibody

HY-P81417

10 μL;50 μL;100 μL

70;185;300 USD

recombinant

domestic rabbit

nonconjugated

YA1162

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

Granulin Antibody

antibody

Rabbit

Monoclonal, Recombinant

Non-conjugated

YA1162

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorirelated genesis.

Acrogranin; CLN11; GEP; GP88; Granulins; GRN; PCDGF; PEPI; PGRN; Proepithelin; Progranulin

A synthesized peptide derived from human Granulin.

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

WB, IHC-P, ICC/IF, IP, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.