antibody

HP1 alpha Antibody

HY-P81280

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

mouse

nonconjugated

YA981

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

HP1 alpha Antibody

antibody

Mouse

Monoclonal

Non-conjugated

YA981

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

The related gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The related gene has a pseudorelated gene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha

Purified recombinant human HP1 alpha protein fragments expressed in E.coli.

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

WB, IHC-F, IHC-P, ICC/IF

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.