product summary
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company name :
MedChem Express LLC
product type :
antibody
product name :
TWIST Antibody
catalog :
HY-P81173
quantity :
10 μL;50 μL;100 μL
price :
95;250;400 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
YA3398
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
Catalog Number :
HY-P81173
Product Name :
TWIST Antibody
Product Type :
antibody
Host Species :
Rabbit
Clonality :
Monoclonal
Conjugation :
Non-conjugated
Clone Name :
YA3398
Size :
10 μL;50 μL;100 μL
List Price :
95;250;400 USD
Product Description :
Primary Antibodies
CrossReactivity :
Human, Mouse
Background :
The related gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of related genes involved in cranial suture closure during skull development. The protein may also regulate neural tube closure, limb development and brown fat metabolism. The related gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. Mutations in The related gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism.
ALTnames :
ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; Class A basic helix-loop-helix protein 38; CRS1; H-twist; OTTHUMP00000116043; SCS; Twist basic helix loop helix transcription factor 1; Twist homolog 1 (Drosophila); Twist homolog 1; TWIST homolog of drosophila; Twist related protein 1; Twist-related protein 1; Twist1; TWST1_HUMAN.
Immunogen :
KLH conjugated synthetic peptide derived from human TWIST: 71-17//2/2
Localization :
Nucleus.
Buffer :
Supplied in PBS with 0.05% sodium azide.
Application Summary :
WB, IHC-P, ICC/IF, FC
Storage :
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA