product summary
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company name :
MedChem Express LLC
product type :
antibody
product name :
MCP1 Antibody
catalog :
HY-P81171
quantity :
10 μL;50 μL;100 μL
price :
75;200;325 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog Number :
HY-P81171
Product Name :
MCP1 Antibody
Product Type :
antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Non-conjugated
Size :
10 μL;50 μL;100 μL
List Price :
75;200;325 USD
Product Description :
Primary Antibodies
CrossReactivity :
Human, Rat
Background :
The related gene is one of several cytokine related genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. The chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. The cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathorelated genesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) infection.
ALTnames :
MCP-1/CCL2; C-C motif chemokine 2; CCL 2; CCL2; CCL2_HUMAN; Chemokine (C C motif) ligand 2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF-2; GDCF2; HC11; HSMCR30; HSMCR30; JE; MCAF; MCP 1; MCP-1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); Small inducible cytokine A2; Small inducible cytokine subfamily A (Cys Cys), member 2; Small inducible cytokine subfamily A Cys Cys member 2; Small-inducible cytokine A2; SMC CF; SMC-CF; SMCCF.
Immunogen :
KLH conjugated synthetic peptide derived from human MCP-1: 24-99/99
Localization :
Secreted.
Buffer :
Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Application Summary :
WB, ELISA, IHC-P, IHC-F, FC, ICC/IF
Storage :
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA