antibody

Fbx32 Antibody

HY-P81082

10 μL;50 μL;100 μL

75;200;325 USD

recombinant

domestic rabbit

nonconjugated

YA919

western blot, immunocytochemistry

Fbx32 Antibody

antibody

Rabbit

Recombinant, Monoclonal

Non-conjugated

YA919

10 μL;50 μL;100 μL

75;200;325 USD

Primary Antibodies

Human, Mouse, Rat

The related gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by The related gene belongs to the Fbxs class and contains an F-box domain. The protein is highly expressed during muscle atrophy, whereas mice deficient in The related gene were found to be resistant to atrophy. The protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Fbx32; 4833442G10Rik; AI430017; Atrogin 1; Atrogin-1; ATROGIN1; Atrophy gene 1; F box only protein 32; F-box only protein 32; F-box protein 32; FBX32_HUMAN; fbxo25; FBXO32; FLJ32424; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F box; Muscle atrophy F box protein; Muscle atrophy F-box protein.

Recombinant protein within Human Fbx32 aa 1-160 / 355.

Cytoplasm. Nucleus.

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

WB;ICC/IF

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.