TRAF6 Antibody | MedChem Express LLC HY-P80919 product information

product summary

company name :

MedChem Express LLC

product type :

antibody

product name :

TRAF6 Antibody

catalog :

HY-P80919

quantity :

10 μL;50 μL;100 μL

price :

70;185;300 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

YA031

reactivity :

human

application :

western blot

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P80919

Product Name :

TRAF6 Antibody

Product Type :

antibody

Host Species :

Rabbit

Clonality :

Monoclonal Antibody

Conjugation :

Unconjugated

Clone Name :

YA031

Size :

10 μL;50 μL;100 μL

List Price :

70;185;300 USD

Product Description :

Primary Antibodies

CrossReactivity :

Human, Rat

Background :

TRAF6: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain and mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. The protein encoded by this gene is a key molecule in antiviral innate and antigen-specific immune responses. [provided by RefSeq, Nov 2021]

ALTnames :

TRAF6; RNF85; TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85

Immunogen :

Synthetic peptide corresponding to Human TRAF6.The exact sequence is proprietary to MCE.

Buffer :

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Application Summary :

Storage :

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

more info or order :

MedChem Express LLC product webpage