antibody

STAT3 Antibody

HY-P80902

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

mouse

nonconjugated

YA666

western blot, immunohistochemistry - paraffin section

STAT3 Antibody

antibody

Mouse

Monoclonal Antibody

Unconjugated

YA666

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Rat, Mouse

STAT3 (6H10): The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020]

STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor

Synthetic peptide corresponding to human STAT3.The exact sequence is proprietary to MCE.

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

WB, IHC-P

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.