Proteasome beta 8 Antibody | MedChem Express LLC HY-P80876 product information

product summary

company name :

MedChem Express LLC

product type :

antibody

product name :

Proteasome beta 8 Antibody

catalog :

HY-P80876

quantity :

10 μL;50 μL;100 μL

price :

70;185;300 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

YA684

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P80876

Product Name :

Proteasome beta 8 Antibody

Product Type :

antibody

Host Species :

Mouse

Clonality :

Monoclonal Antibody

Conjugation :

Unconjugated

Clone Name :

YA684

Size :

10 μL;50 μL;100 μL

List Price :

70;185;300 USD

Product Description :

Primary Antibodies

CrossReactivity :

Human, Rat

Background :

Proteasome beta 8 (3G3): The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008]

ALTnames :

PSMB8; LMP7; PSMB5i; RING10; Y2; Proteasome subunit beta type-8; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting

Immunogen :

Synthetic peptide corresponding to Human PSMB8.The exact sequence is proprietary to MCE.

Buffer :

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Application Summary :

WB, IHC-F, IHC-P, ICC/IF

Storage :

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

more info or order :

MedChem Express LLC product webpage