product summary
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company name :
MedChem Express LLC
product type :
antibody
product name :
Phospho-ATF2 Antibody
catalog :
HY-P80793
quantity :
10 μL;50 μL;100 μL
price :
70;185;300 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
YA224
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
product information
Catalog Number :
HY-P80793
Product Name :
Phospho-ATF2 Antibody
Product Type :
antibody
Host Species :
Rabbit
Clonality :
Monoclonal Antibody
Conjugation :
Unconjugated
Clone Name :
YA224
Size :
10 μL;50 μL;100 μL
List Price :
70;185;300 USD
Product Description :
Primary Antibodies
CrossReactivity :
Human, Mouse
Background :
ATF2: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
ALTnames :
ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro
Immunogen :
Synthetic phosphopeptide corresponding to residues surrounding Thr71 of Human ATF2.The exact sequence is proprietary to MCE.
Buffer :
Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
Application Summary :
WB, ICC/IF, IP
Storage :
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA