MLH1 Antibody | MedChem Express LLC HY-P80753 product information

product summary

company name :

MedChem Express LLC

product type :

antibody

product name :

MLH1 Antibody

catalog :

HY-P80753

quantity :

10 μL;50 μL;100 μL

price :

100;270;430 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

YA703

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P80753

Product Name :

MLH1 Antibody

Product Type :

antibody

Host Species :

Mouse

Clonality :

Monoclonal Antibody

Conjugation :

Unconjugated

Clone Name :

YA703

Size :

10 μL;50 μL;100 μL

List Price :

100;270;430 USD

Product Description :

Primary Antibodies

CrossReactivity :

Human, Monkey

Background :

MLH1 (4C1): The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). [provided by RefSeq, Aug 2017]

ALTnames :

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Immunogen :

Synthetic peptide corresponding to MLH1.AA range:381-483.

Buffer :

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Application Summary :

WB, ICC/IF

Storage :

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

more info or order :

MedChem Express LLC product webpage