antibody

Collagen I alpha 2 Antibody

HY-P80627

10 μL;50 μL;100 μL

75;202;325 USD

polyclonal

domestic rabbit

nonconjugated

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

Collagen I alpha 2 Antibody

antibody

Rabbit

Polyclonal Antibody

Unconjugated

10 μL;50 μL;100 μL

75;202;325 USD

Primary Antibodies

Human, Mouse, Rat

Collagen I alpha 2: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Collagen alpha-2(I) chain (Alpha-2 type I collagen)

Synthetic peptide corresponding to Human Collagen I.AA range:1-50

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

WB, IHC-F, IHC-P, ICC/IF, ELISA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.