antibody

CD45 Antibody

HY-P80603

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

mouse

nonconjugated

YA800

western blot, immunohistochemistry - paraffin section

CD45 Antibody

antibody

Mouse

Monoclonal Antibody

Unconjugated

YA800

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse

CD45: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45

Synthetic peptide corresponding to Human PTPRC.AA range:928-989.

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

WB, IHC-P

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.