antibody

Caspase 11 Antibody

HY-P80588

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

domestic rabbit

nonconjugated

YA562

western blot, immunoprecipitation

Caspase 11 Antibody

antibody

Rabbit

Monoclonal Antibody

Unconjugated

YA562

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human, Mouse, Rat

Caspase 11: This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]

Caspl; ich-3; CASP-4; Casp11; CASP-11

Synthetic peptide corresponding to Mouse Caspase-11.The exact sequence is proprietary to MCE.

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

WB, IP

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.