antibody

AIF Antibody

HY-P80534

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

mouse

nonconjugated

YA835

western blot, immunocytochemistry

AIF Antibody

antibody

Mouse

Monoclonal Antibody

Unconjugated

YA835

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

AIF (8H1): This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]

AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8

Synthetic peptide corresponding to Human AIF.The exact sequence is proprietary to MCE.

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

WB, ICC/IF

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.