antibody

TMS1 Antibody

HY-P80522

10 μL;50 μL;100 μL

70;185;300 USD

monoclonal

domestic rabbit

nonconjugated

YA033

western blot, immunocytochemistry, flow cytometry

TMS1 Antibody

antibody

Rabbit

Monoclonal Antibody

Unconjugated

YA033

10 μL;50 μL;100 μL

70;185;300 USD

Primary Antibodies

Human

The related gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, The protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for The related gene.

PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1

Synthetic peptide corresponding to Human TMS1.AA range:121-170.

Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Inflammasome, Membrane, Mitochondrion, Nucleus.

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

WB, ICC/IF, FC

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.