antibody

BAX Antibody

HY-P80027

10 μL;50 μL;100 μL

130;340;550 USD

monoclonal

mouse

nonconjugated

YA825

western blot, immunohistochemistry - paraffin section

BAX Antibody

antibody

Mouse

Monoclonal Antibody

Unconjugated

YA825

10 μL;50 μL;100 μL

130;340;550 USD

Primary Antibodies

Human, Mouse, Rat

BAX: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Synthetic peptide corresponding to Human BAX.The exact sequence is proprietary to MCE.

Mitochondrion membrane, cytoplasm

Supplied in 1*PBS (pH7.4), 0.2% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

WB, IHC-P

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.