53BP1 Antibody | MedChem Express LLC HY-P80001 product information

product summary

company name :

MedChem Express LLC

product type :

antibody

product name :

53BP1 Antibody

catalog :

HY-P80001

quantity :

10 μL;50 μL;100 μL

price :

92;245;400 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

YA649

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P80001

Product Name :

53BP1 Antibody

Product Type :

antibody

Host Species :

Rabbit

Clonality :

Monoclonal Antibody

Conjugation :

Unconjugated

Clone Name :

YA649

Size :

10 μL;50 μL;100 μL

List Price :

92;245;400 USD

Product Description :

Primary Antibodies

CrossReactivity :

Human, Mouse, Rat

Background :

TP53BP1: This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

Immunogen :

Synthetic peptide corresponding to Human 53BP1.AA range:1-50.

Localization :

Nucleus. Chromosome.

Buffer :

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

Application Summary :

WB, ICC/IF, IHC-P, FC

Storage :

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

more info or order :

MedChem Express LLC product webpage