protein

ACE/CD143 Protein, Human (His)

HY-P7992

10 μg;50 μg

135;325 USD

ACE/CD143 Protein, Human (His)

proteins

E. coli

10 μg;50 μg

135;325 USD

ACE/CD143 Protein, Human (His) is a recombinant human Angiotensin-converting enzyme/CD143 a His tag at the C-terminus. Angiotensin I-converting enzyme (ACE, CD143) hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity [1] .

Human

ACE is a Zn 2+ carboxydipeptidase which plays a key role in the regulation of blood pressure and also in the development of vascular pathologies and tissue remodeling. ACE is expressed as two isoforms: somatic ACE (sACE), which is responsible for its hypertensive properties, and a smaller isoform (testicular ACE), which is expressed solely in germinal cells [1] .

ACE; CD143; DCP; DCP1

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, 2M Urea, pH 7.4.

Room temperature in continental US; may vary elsewhere.