protein

IFN-lambda 2/IL-28A Protein, Mouse (HEK293, His, solution)

HY-P7991

10 μg;50 μg

80;250 USD

IFN-lambda 2/IL-28A Protein, Mouse (HEK293, His, solution)

proteins

HEK293

10 μg;50 μg

80;250 USD

IFN-lambda 2/IL-28A Protein, Mouse (HEK 293, His), a type III interferon, is a member of IL-10-interferon family. IFN-lambda 2/IL-28A Protein shows anti-viral, anti-tumor and immune stimulatory properties.

Mouse

Interferon lambdas (IFN-λs; IFNL1-4) modulate immunity in the context of infections and autoimmune diseases, through a network of induced genes. IL-28A, IL-28B and IL-29 (also designated type III interferons) constitute a new subfamily within the IL-10-interferon family. IL-28A, IL-28B and IL-29 share a common cellular receptor consisting of the cytokine receptor family class II members IL-28R1 (also designated IFN-λR1, LICR2 and CRF2/12) and IL-10R2. IL-28A was shown to reduce viral replication or the cytopathic effect of a range of viruses, including the DNA viruses murine CMV, hepatitis B virus and herpes simplex virus 2, the ss (+) RNA viruses EMCV, west nile virus and hepatitis C virus, as well as the ss (-) RNA viruses vesicular stomatitis virus, influenza-A virus and Hantaan virus [1] [2] .

Interferon-λ2, IFN-λ2, IL-28A

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice.