protein

Janus kinase 2/JAK2 Protein, Human (His)

HY-P7989

5 μg;10 μg;50 μg

88;150;400 USD

Janus kinase 2/JAK2 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

88;150;400 USD

Janus kinase 2/JAK2 Protein, Human (His) is a recombinant human JAK2 expressed in E. coli with a His tag at the N-terminus. JAK2 is a non-receptor tyrosine kinase [1] [2] .

Human

JAK2 is a member of the Janus kinase (JAKs) family of non-receptor protein tyrosine kinases, which includes JAK1-3 and TYK2. JAKs serve as the cytoplasmic signaling components of cytokine receptors and are activated through cytokine-mediated trans-phosphorylation, which leads to receptor phosphorylation and recruitment and phosphorylation of signal transducer and activator of transcription (STAT) proteins. JAKs are non-receptor protein tyrosine kinases that serve as the catalytic signaling components for a wide range of cytokine receptors, including the receptors for interleukins, interferons, growth hormone, erythropoietin, and leptin [1] [2] .

JAK2, Janus kinase 2

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0 or 50 mM Tris-HCL, 200 mM NaCl, 200 mM arginine, 2 mM DTT, pH 8.0.

Shipping with dry ice