product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
IL-10 Protein, Virus
catalog :
HY-P79362
quantity :
5 μg;10 μg;50 μg;100 μg;500 μg;1 mg
price :
110;180;500;800;2240;3600 USD
more info or order :
product information
Catalog Number :
HY-P79362
Product Name :
IL-10 Protein, Virus
Product Type :
proteins
Host Species :
E. coli
Size :
5 μg;10 μg;50 μg;100 μg;500 μg;1 mg
List Price :
110;180;500;800;2240;3600 USD
Product Description :
IL-10 Protein critically masks infected cells for immune evasion by down-regulating the host TAP1 gene, hindering peptide transport into the endoplasmic reticulum and loading onto MHC class I molecules. IL-10 also inhibits IFN-gamma synthesis and exists as a homodimer. IL-10 Protein, Virus is the recombinant Virus-derived IL-10 protein, expressed by E. coli , with tag free.
SpeciesSummary :
Virus
Background :
The IL-10 protein plays a critical role in immune recognition by cytotoxic T-lymphocytes, as it is involved in masking infected cells. It accomplishes this by down-regulating the expression of the host TAP1 gene, which hampers the transport of peptides into the endoplasmic reticulum and their subsequent loading onto MHC class I molecules. Additionally, IL-10 inhibits the synthesis of IFN-gamma. It exists as a homodimer.
ALTnames :
Viral interleukin-10 homolog; BCRF1; vIL-10; 20 kDa protein; Protein BCRF1; Interleukin 10
Purity :
Greater than 95% as determined by reducing SDS-PAGE
Buffer :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 8% trehalose, 8% mannitol and 0.02% Tween80.
Storage :
Room temperature in continental US; may vary elsewhere.
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA