protein

ADAMTS13 Protein, Human (CHO, His)

HY-P79144

5 μg;10 μg;50 μg

175;280;785 USD

ADAMTS13 Protein, Human (CHO, His)

proteins

CHO

5 μg;10 μg;50 μg

175;280;785 USD

The ADAMTS13 protein, a metalloproteinase, has a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. It cleaves von Willebrand Factor and defects in this gene cause thrombotic thrombocytopenic purpura. Alternative splicing generates multiple transcript variants. ADAMTS13 is broadly expressed in various tissues, including the liver, testis, and 24 other tissues. ADAMTS13 Protein, Human (CHO, His) is the recombinant human-derived ADAMTS13, expressed by CHO , with C-10*His labeled tag. The total length of ADAMTS13 Protein, Human (CHO, His) is 655 a.a.,

Human

The ADAMTS13 protein, a member of the metalloproteinase family, contains distinct regions including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This enzyme specifically cleaves von Willebrand Factor (vWF) and defects in this gene are associated with thrombotic thrombocytopenic purpura. Multiple transcript variants are generated through alternative splicing. Additionally, the ADAMTS13 protein exhibits broad expression in various tissues, including the liver, testis, and 24 other tissues.

ADAM-TS 13; ADAM-TS13; ADAMTS-13von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease; A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 13

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.22 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 8.0, 8% trehalose.

Room temperature in continental US; may vary elsewhere.