protein

IL-4 Protein, Bovine

HY-P79117

5 μg;10 μg;50 μg

115;180;500 USD

IL-4 Protein, Bovine

proteins

E. coli

5 μg;10 μg;50 μg

115;180;500 USD

IL-4 Protein, a key participant in B-cell activation and various cell types, acts as a costimulator of DNA synthesis. It induces class II MHC molecules on B-cells, enhances IgE and IgG1 secretion and expression, and regulates CD23 on lymphocytes and monocytes. IL-4 positively regulates IL31RA in macrophages and stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and inducing RUFY4. IL-4 Protein, Bovine is the recombinant bovine-derived IL-4 protein, expressed by E. coli , with tag free.

Bovine

IL-4 protein actively participates in multiple B-cell activation processes and influences various cell types as a critical regulator. Functioning as a costimulator, IL-4 stimulates DNA synthesis and induces the expression of class II MHC molecules on resting B-cells. Furthermore, it plays a pivotal role in enhancing both the secretion and cell surface expression of IgE and IgG1, contributing to immune responses. IL-4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on lymphocytes and monocytes. Beyond its effects on B-cells, IL-4 positively regulates IL31RA expression in macrophages, further diversifying its immunomodulatory functions. Additionally, IL-4 stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and inducing RUFY4, underscoring its intricate involvement in cellular processes across different immune cell types.

Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1; Interleukin 4

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.