protein

BMP-3 Protein, Human

HY-P79077

2 μg;10 μg;50 μg;100 μg

32;90;250;400 USD

BMP-3 Protein, Human

Protein

E. coli

2 μg;10 μg;50 μg;100 μg

32;90;250;400 USD

BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. BMP-3 Protein, Human is the recombinant human-derived BMP-3 protein, expressed by E. coli , with tag free.