protein

NucA Protein, S. marcescens

HY-P78955

5 μg;10 μg;50 μg

72;115;300 USD

NucA Protein, S. marcescens

proteins

E. coli

5 μg;10 μg;50 μg

72;115;300 USD

The NucA protein plays a central role in cellular processes because it catalyzes the hydrolysis of DNA and RNA (both double- and single-stranded) at the 3' position of the phosphodiester bond to generate 5'-phosphorylated single- and double-stranded , tri- and tetra-nucleotides. This multifunctional enzymatic activity emphasizes the importance of NucA in nucleic acid metabolism, as observed in various studies. NucA Protein, S. marcescens is the recombinant NucA protein, expressed by E. coli , with tag free. The total length of NucA Protein, S. marcescens is 266 a.a., with molecular weight of ~29 kDa.

Others

NucA is an enzyme that catalyzes the hydrolysis of both DNA and RNA, targeting the 3' position of the phosphodiester bond and producing 5'-phosphorylated mono-, di-, tri-, and tetranucleotides. It exhibits activity on both double- and single-stranded nucleic acids, with DNA being a slightly more favorable substrate compared to RNA. NucA's ability to cleave phosphodiester bonds in nucleic acids results in the generation of smaller nucleotide fragments. This enzymatic activity suggests a role in nucleic acid metabolism, potentially contributing to the turnover and recycling of nucleotide components within the cell. It has to succinctly describe NucA's substrate specificity and its capacity to hydrolyze both DNA and RNA at the 3' position of the phosphodiester bond, emphasizing its role in nucleic acid cleavage.

Nuclease; nucA; Endonuclease; nuc; Benzonase Nuclease

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 200 mM NaCl, pH 8.0.

Shipping with dry ice