protein

Fractalkine/CX3CL1 Protein, Human (Biotinylated, HEK293, His)

HY-P78937

5 μg;10 μg;50 μg

118;200;560 USD

Fractalkine/CX3CL1 Protein, Human (Biotinylated, HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

118;200;560 USD

Fractalkine/CX3CL1 is a chemokine that acts as a ligand to CX3CR1 and the integrins ITGAV: ITGB3 and ITGA4: ITGB1. CX3CL1 promotes lung cancer cell migration and invasion through the Src/FAK signaling pathway. CX3CL1 plays an important role in immune response, inflammation, cell adhesion and chemotaxis. Fractalkine/CX3CL1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-Avi, C-10*His labeled tag.

Human

Fractalkine/CX3CL1 is a chemokine that acts as a ligand to CX3CR1 and the integrins ITGAV: ITGB3 and ITGA4: ITGB1. CX3CR1-CX3CL1 signaling performs different functions in different tissue comparators, such as immune response, inflammation, cell adhesion, and chemotaxis. CX3CL1 regulates endothelial cell adhesion and migration and activates integrins through CX3Cr1-dependent and CXCr1-independent activation. CX3CL1 promotes lung cancer cell migration and invasion through the Src/FAK signaling pathway [1] [2] [3] .

Fractalkine; Neurotactin; Cx3cl1; Cx3c; Fkn; ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.