protein

4-1BBL/TNFSF9 Protein, Human (Biotinylated, HEK293, Fc-Avi)

HY-P78933

5 μg;10 μg;50 μg

125;215;500 USD

4-1BBL/TNFSF9 Protein, Human (Biotinylated, HEK293, Fc-Avi)

proteins

HEK293

5 μg;10 μg;50 μg

125;215;500 USD

4-1BBL/TNFSF9 protein is a cytokine that selectively binds to TNFRSF9 and exerts its effects by inducing the proliferation of activated peripheral blood T cells. As a homotrimer, this ligand demonstrates its potential role in activation-induced cell death (AICD) and may be involved in coordinating homologous interactions between T cells and B cells/macrophages. 4-1BBL/TNFSF9 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived 4-1BBL/TNFSF9 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of 4-1BBL/TNFSF9 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 205 a.a., with molecular weight of 50-55 kDa.

Human

The 4-1BBL (TNFSF9) protein is a cytokine with significant immunomodulatory functions, binding to the TNFRSF9 receptor. Its interaction induces the proliferation of activated peripheral blood T-cells, suggesting a role in T-cell activation and immune response amplification. Additionally, 4-1BBL may be involved in activation-induced cell death (AICD), a process that regulates the survival and homeostasis of activated immune cells. Furthermore, the protein might play a role in mediating cognate interactions between T-cells and B-cells/macrophages, contributing to immune cell communication and coordination. Structurally, 4-1BBL forms homotrimers, indicating its organization into trimeric complexes. These diverse functions underscore the pivotal role of 4-1BBL in immune regulation and intercellular communication within the immune system.

4-1BB Ligand; TNFSF9; CD137L

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of PBS,6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.