protein

Serum Albumin/ALB Protein, Rabbit (HEK293, His)

HY-P78737

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;56;118;200;560;952 USD

Serum Albumin/ALB Protein, Rabbit (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;56;118;200;560;952 USD

ALB protein is a serum protein synthesized by the liver and plays a vital role in maintaining body fluid balance and transporting various molecules in the blood. It is involved in the regulation of osmotic pressure and acts as a carrier for hormones, fatty acids, and drugs. Serum Albumin/ALB Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived Serum Albumin/ALB protein, expressed by HEK293 , with C-His labeled tag. The total length of Serum Albumin/ALB Protein, Rabbit (HEK293, His) is 584 a.a., with molecular weight of 60-70 kDa.

Rabbit

ALB Protein, a versatile molecule, binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its primary role is to regulate the colloidal osmotic pressure of blood. Acting as a major zinc transporter in plasma, it binds around 80% of all plasma zinc, while also functioning as a major calcium and magnesium transporter, binding approximately 45% of circulating calcium and magnesium in plasma. ALB Protein may possess multiple calcium-binding sites and can potentially bind calcium in a non-specific manner. The interaction between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. Its affinity follows the rank order of zinc > calcium > magnesium. Furthermore, ALB Protein interacts with the bacterial siderophore enterobactin, inhibiting its iron uptake and potentially limiting the growth of enteric bacteria such as E.coli. Notably, it does not hinder iron uptake by the bacterial siderophore aerobactin. ALB Protein also plays a role in ALB homeostasis through its interaction with FCGRT, and it interacts with TASOR as well. In plasma, ALB Protein forms a covalently-linked complex with chromophore-bound alpha-1-microglobulin, without impeding the binding of fatty acids to ALB.

Serum albumin; ALB; Alb

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.