protein

Growth Hormone R/GHR Protein, Rhesus macaque (HEK293, Fc)

HY-P78726

5 μg;10 μg;50 μg;100 μg

41;69;194;330 USD

Growth Hormone R/GHR Protein, Rhesus macaque (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

41;69;194;330 USD

GHR Protein, a cell surface receptor, is involved in growth regulation and metabolism. Dysregulation of GHR Protein has been linked to conditions such as growth hormone deficiency and metabolic disorders. Targeting GHR Protein may offer potential therapeutic interventions in these conditions by regulating growth, improving metabolism, and managing related disorders. Growth Hormone R/GHR Protein, Rhesus macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag.

Rhesus Macaque

The GHR protein, a receptor for pituitary gland growth hormone, plays a crucial role in regulating postnatal body growth. Upon binding to its ligand, GHR activates the JAK2/STAT5 pathway, thereby initiating downstream signaling events. Additionally, the soluble form of GHR, known as GHBP, functions as a reservoir for growth hormone in the plasma and may serve as a modulator or inhibitor of GH signaling.

GHR; GHBP; GH receptor

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5.

Room temperature in continental US; may vary elsewhere.