protein

AMHR2/MISRII Protein, Mouse (HEK293, His)

HY-P78693

5 μg;10 μg

59;100 USD

AMHR2/MISRII Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg

59;100 USD

The AMHR2/MISRII protein assembles receptor complexes with two type II and two type I transmembrane serine/threonine kinases upon ligand binding. Type II receptors initiate signaling cascades by phosphorylating and activating type I receptors, which undergo autophosphorylation. AMHR2/MISRII Protein, Mouse (HEK293, His) is the recombinant mouse-derived AMHR2/MISRII protein, expressed by HEK293 , with C-His labeled tag. The total length of AMHR2/MISRII Protein, Mouse (HEK293, His) is 132 a.a., with molecular weight of approximately 25 kDa & 30 kDa, respectively.

Mouse

Upon binding its ligand, AMHR2/MISRII Protein orchestrates the assembly of a receptor complex comprising two type II and two type I transmembrane serine/threonine kinases. The type II receptors initiate the signaling cascade by phosphorylating and activating the type I receptors, which, in turn, undergo autophosphorylation. Subsequently, these activated type I receptors engage with and activate SMAD transcriptional regulators, culminating in the modulation of downstream gene expression. Notably, AMHR2/MISRII serves as the receptor for anti-Muellerian hormone, playing a pivotal role in mediating the cellular responses triggered by this hormone.

MIS RII; MRII; AMHR2; AMHR; MISR2; AMH type II receptor

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.