protein

PLGF Protein, Rhesus macaque (HEK293, His)

HY-P78688

2 μg;10 μg;50 μg;100 μg

41;114;320;544 USD

PLGF Protein, Rhesus macaque (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

41;114;320;544 USD

PLGF protein is an important growth factor in angiogenesis and endothelial cell growth, stimulating cell proliferation and migration by binding to the FLT1/VEGFR-1 receptor. PLGF plays a crucial role in angiogenesis and also contributes to tumor growth, highlighting its involvement in pathological angiogenesis. PLGF Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived PLGF protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of PLGF Protein, Rhesus macaque (HEK293, His) is 152 a.a., with molecular weight of ~28-32 kDa.

Rhesus Macaque

The PLGF Protein, a growth factor integral to angiogenesis and endothelial cell growth, exhibits stimulatory effects on both proliferation and migration of these cells. Functioning through its binding to the FLT1/VEGFR-1 receptor, PLGF plays a crucial role in orchestrating angiogenic processes. Additionally, it contributes to tumor growth, emphasizing its involvement in pathological angiogenesis. Structurally, PLGF exists as an antiparallel homodimer, connected by disulfide linkages. Furthermore, it can form heterodimers with VEGFA/VEGF, suggesting a dynamic role in the regulation of vascular growth and function. The multifaceted actions and structural arrangements of PLGF underscore its significance in modulating vascular processes and tumor development.

PGF; PLGF; PlGF2; PlGF; PGFL; SHGC-10760

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Room temperature in continental US; may vary elsewhere.