protein

DKK-3 Protein, Human (R335G, HEK293, His)

HY-P78681

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

DKK-3 Protein, Human (R335G, HEK293, His)

Protein

HEK293

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interactions and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization.In vertebrate development, DKK-3, together with other DKKs, critically inhibits Wnt-regulated processes such as axial patterning, limb development, somitogenesis, and eye formation.DKK-3 Protein, Human (R335G, HEK293, His) is the recombinant human-derived DKK-3 protein, expressed by HEK293 , with C-6*His labeled tag and R335G, , , , mutation.