protein

Cystatin SN/CST1 Protein, Human (HEK293, His)

HY-P7867

10 μg;50 μg

160;450 USD

Cystatin SN/CST1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

160;450 USD

Cystatin SN (CST1) is a component of human saliva that is immunologically similar to cystatin S but exhibits distinct specificity due to sequence variation. Cystatin SN has an isoelectric point of 7.5 and is a potent inhibitor of papain and dipeptidyl peptidase I, superior to Cystatin S in these activities. Cystatin SN/CST1 Protein, Human (HEK293, His) is the recombinant human-derived Cystatin SN/CST1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cystatin SN/CST1 Protein, Human (HEK293, His) is 121 a.a., with molecular weight of ~17.0 kDa.

Human

Cystatin SN (CST1), a component of human saliva, belongs to the cysteine proteinase inhibitor family, sharing immunological similarity with cystatin S. Despite this similarity, Cystatin SN exhibits distinct specificity due to amino acid sequence variations. With a pI of 7.5, Cystatin SN stands out as a potent inhibitor of papain and dipeptidyl peptidase I, outperforming cystatin S in these inhibitory activities. Notably, both Cystatin SN and cystatin S demonstrate equal proficiency in inhibiting ficin. This highlights the intricate variations in the inhibitory capabilities within the cystatin family present in saliva, emphasizing their potential roles in regulating specific proteolytic activities.

rHuCystatin-SN/CST1, His; Cystatin-SN; Cystain-SA-I; Cystatin-1; Salivary Cystatin-SA-1; CST1

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5 or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.