protein

PTK7 Protein, Rabbit (HEK293, His)

HY-P78603

5 μg;10 μg;50 μg;100 μg

40;68;190;320 USD

PTK7 Protein, Rabbit (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;68;190;320 USD

The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived PTK7 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PTK7 Protein, Rabbit (HEK293, His) is 582 a.a., with molecular weight of approximately 110 kDa.

Rabbit

The PTK7 protein, an inactive tyrosine kinase, plays a significant role in the Wnt signaling pathway, being a component of both the non-canonical (Wnt/planar cell polarity signaling) and canonical Wnt signaling pathways. Its involvement spans diverse cellular processes, including cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 also contributes to critical developmental events, such as embryogenesis, epithelial tissue organization, and angiogenesis. Notably, it interacts with CTNNB1, underlining its participation in Wnt pathway regulation and its impact on cellular functions with broader implications in both normal and pathological contexts.

PTK7; CCK4; CCK-4; Tyrosine-protein kinase-like 7; Protein-tyrosine kinase 7; Protein-tyrosine kinase 7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.