protein

TL1A/TNFSF15 Trimer Protein, Human (HEK293, His-Flag)

HY-P78447

2 μg;10 μg;20 μg;50 μg;100 μg;250 μg;500 μg;1 mg

42;110;175;380;684;1160;1750;2800 USD

TL1A/TNFSF15 Trimer Protein, Human (HEK293, His-Flag)

Protein

HEK293

2 μg;10 μg;20 μg;50 μg;100 μg;250 μg;500 μg;1 mg

42;110;175;380;684;1160;1750;2800 USD

The TL1A protein (VEGI protein), belongs to the tumor necrosis factor (TNF) family and is a receptor for TNFRSF25 and TNFRSF6B. TL1A is involved in the activation of NF-κB and C-Jun pathways, which can be used as a regulator of mucosal immunity and participate in the immune pathway of inflammatory bowel disease (IBD) pathogenesis. TL1A originates from endothelial cells and inhibits the proliferation of breast cancer, epithelial and myeloid tumor cells. The human TL1A protein has a transmembrane domain (36-56 a.a.) that can be cleaved into membrane-type and soluble peptide fragments. TL1A/TNFSF15 Trimer Protein, Human (HEK293, His-Flag) is the extracullar part of TL1A protein (D91-L251), produced in HEK293 cells with N-terminal His- and Flag-tag.