protein

2B4/CD244 Protein, Human (HEK293, Fc)

HY-P78366

20 μg;50 μg

90;200 USD

2B4/CD244 Protein, Human (HEK293, Fc)

proteins

HEK293

20 μg;50 μg

90;200 USD

2B4/CD244 protein exhibits heightened affinity for binding to CD48, surpassing isoform 1, leading to increased cytotoxicity and intracellular calcium release. The stronger interaction implies more robust engagement, potentially amplifying cellular responses, particularly heightened cytotoxic activity and intracellular calcium release. 2B4/CD244 Protein, Human (200a.a, HEK293, Fc) is the recombinant human-derived 2B4/CD244 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of 2B4/CD244 Protein, Human (200a.a, HEK293, Fc) is 200 a.a., with molecular weight of 49 kDa.

Human

The 2B4/CD244 protein demonstrates a higher affinity for binding to CD48 compared to isoform 1, and this interaction results in heightened cytotoxicity and intracellular calcium release. The stronger binding between 2B4/CD244 and CD48 suggests a more robust engagement, potentially leading to enhanced cellular responses, including increased cytotoxic activity and release of intracellular calcium.

2B4; CD244 antigen; CD244; h2B4; NAIL; NKR2B4; Nmrk; SLAMF4

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization

Room temperature in continental US; may vary elsewhere.