protein

Galectin-1/LGALS1 Protein, Mouse (HEK293, Fc)

HY-P78301

5 μg;10 μg;50 μg;100 μg

55;95;265;450 USD

Galectin-1/LGALS1 Protein, Mouse (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

55;95;265;450 USD

Galectin-1/LGALS1 protein is a β-galactoside-binding lectin that regulates apoptosis, cell proliferation, and differentiation by inhibiting CD45 protein phosphatase.It prevents Lyn kinase dephosphorylation, induces T cell apoptosis as a homodimer, and interacts with CD2, CD3, CD4, CD6, CD7, CD43, ALCAM and CD45.Galectin-1/LGALS1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Galectin-1/LGALS1 protein, expressed by HEK293 , with N-hFc labeled tag.

Mouse

Galectin-1/LGALS1 Protein functions as a versatile lectin with a high affinity for beta-galactoside and a diverse range of complex carbohydrates. Its pivotal role extends to the regulation of apoptosis, cell proliferation, and cell differentiation. Notably, Galectin-1/LGALS1 acts as an inhibitor of CD45 protein phosphatase activity, thereby preventing the dephosphorylation of Lyn kinase. Furthermore, it serves as a potent inducer of T-cell apoptosis and exists as a homodimer. The protein engages in various interactions, binding to LGALS3BP and interacting with cell surface proteins such as CD2, CD3, CD4, CD6, CD7, CD43, ALCAM, and CD45. Galectin-1/LGALS1 also forms associations with laminin through poly-N-acetyllactosamine binding and interacts with SUSD2. A noteworthy interaction occurs with the cargo receptor TMED10, facilitating translocation from the cytoplasm into the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and subsequent secretion.

Galectin-1; HLBP14; S-Lac lectin 1; LGALS1; GAL1; GBP; DKFZp686E23103

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.