protein

Fc gamma RIIA/CD32a Protein, Cynomolgus (HEK293, His)

HY-P78265

20 μg;50 μg

110;240 USD

Fc gamma RIIA/CD32a Protein, Cynomolgus (HEK293, His)

proteins

HEK293

20 μg;50 μg

110;240 USD

Fc gamma RIIA/CD32a protein belongs to the FC family of receptor proteins and is a type 1 transmembrane glycoprotein that binds immunoglobulin subtypes IgG1-4 and can bind c-reactive protein (CRP) with high affinity. It plays an important role in immune regulation in many infections, including malaria. Fc gamma RIIA/CD32a Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIIA/CD32a Protein, Cynomolgus (HEK293, His) is 181 a.a., with molecular weight of 30-40 kDa.

Cynomolgus

Fc gamma RIIA/CD32a Protein contains a polymorphic variant (H/R131) that is associated with susceptibility variability in bacterial diseases and Plasmodium falciparum parasitemia. Fc gamma RIIA/CD32a Protein is a low-affinity IgG receptor that binds immunoglobulin subtypes IgG1-4 and can bind c-reactive protein (CRP) with high affinity, playing an important role in immune regulation [1] . Fc gamma RIIA/CD32a Protein inhibits the production of type I and type III Interferons in human marrow immune cells [2] . Fc gamma RIIA/CD32a protein promotes phagocytosis of opsonized antigens, further promoting immune defense mechanisms [3] .

CD32MGC23887; CDw32fc-gamma-RIIa; Fc gamma RIIA; FCG2; Fc-gamma-RIIa; FcGR; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; IGFR2MGC30032; IgG Fc receptor II-a; FCG2; CD32A

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.