CEACAM7 Protein, Human (HEK293, His) | MedChem Express LLC HY-P7825 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

CEACAM7 Protein, Human (HEK293, His)

catalog :

HY-P7825

quantity :

10 μg;50 μg

price :

165;496 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7825

Product Name :

CEACAM7 Protein, Human (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

165;496 USD

Product Description :

CEAM7/CEACAM7 belongs to the class of carcinoembryonic antigen (CEA) proteins, a cell surface glycoprotein. CEACAM7 is dysregulated in hyperplastic colorectal polyps and early adenomas and may serve as a potential early diagnostic and/or prognostic marker for pancreatic cancer (PanCa) or pancreatic ductal adenocarcinoma (PDAC). CEACAM7 Protein, Human (HEK293, His) is the recombinant human-derived CEACAM7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CEACAM7 Protein, Human (HEK293, His) is 107 a.a., with molecular weight of 20-30 kDa.

SpeciesSummary :

Human

Background :

CEAM7/CEACAM7 are cell surface glycoproteins belonging to the carcinoembryonic antigen (CEA) protein family. Carcinoembryonic antigen (CEA) is a classic colorectal cancer tumor marker, such as CEACAM1, CEACAM5, and CEACAM6, which are considered effective clinical biomarkers and therapeutic targets for melanoma, lung, colorectal, and pancreatic cancer. CEACAM5, CEACAM6, CEACAM7, and CEACAM8 are associated with the cell membrane through GPI connections. Among them, CEACAM6 and CEACAM7 are differentially expressed in normal tissues and dysregulated in hyperplastic colorectal polyps and early adenomas. The expression of CEACAM7 may be downregulated in colon and rectal cancers or may predict rectal cancer recurrence. There is an association between higher expression of CEACAM7 and poor prognosis in patients with a high risk ratio and may serve as a potential early diagnostic and/or prognostic marker for pancreatic ductal adenocarcinoma (PDAC).

ALTnames :

rHuCarcinoembryonic antigen-related cell adhesion molecule 7/CEACAM7, His; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7; Carcinoembryonic Antigen CGM2; CEACAM7; CGM2

Purity :

Greater than 95% as determined by reducing SDS-PAGE

Buffer :

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage