protein

CCL24/Eotaxin-2 Protein, Mouse (HEK293, His)

HY-P78248

5 μg;10 μg;50 μg

95;160;440 USD

CCL24/Eotaxin-2 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

95;160;440 USD

CCL24/Eotaxin-2 Protein, Mouse (HEK293, His) is a CC chemokine that interacts with the chemokine receptor CCR3 to induce eosinophil chemotaxis and mediate atopic diseases, parasitic infections and systemic diseases, as well as promote cellular transport and regulate inflammatory and fibrotic activities. CCL24/Eotaxin-2 Protein, Mouse (HEK293, His) is a recombinant mouse CCL24/Eotaxin-2 (V27-V119) protein expressed by HEK293 with a his tag at the N-terminus [1] .

Mouse

CCL24, also known as eosinophil chemotactic protein 2 (eotaxin-2) and myeloid progenitor inhibitory factor 2 (MPIF-2), is a small cytokine of the CC chemokine family, located on chromosome 7 in the human genome. CCL24 is highly chemotactic for resting T lymphocytes and eosinophils and has low chemotactic activity for neutrophils, but not for monocytes and activated lymphocytes. By binding to its sole receptor CCR3, of which CCR3, is present mainly on eosinophils, but also on basophils, monocytes, Th2 lymphocytes, epithelial cells and airway smooth muscle. CCL24 mainly mediates atopic diseases, parasitic infections and systemic diseases, but also promotes cellular transport and regulates inflammatory and fibrotic activities [1] [2] .

CK-beta-6; Eotaxin-2; MPIF-2; MPIF2; SCYA24; Ckb-6; CCL24; member 24; CK-β-6

Greater than 95% as determined by Tris-Bis PAGE.

Supplied as a 0.22 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 7.5.

Shipping with dry ice