protein

Endoglycan/PODXL2 Protein, Human (HEK293, His)

HY-P78020

20 μg;50 μg

145;320 USD

Endoglycan/PODXL2 Protein, Human (HEK293, His)

proteins

HEK293

20 μg;50 μg

145;320 USD

The endocan/PODXL2 protein serves as a ligand for angioselectin, enabling leukocytes to rapidly roll on the vascular surface through high-affinity divalent cation-dependent interactions with E-, P-, and L-selectin. Through disulfide bonds, the protein forms homodimers and interacts with specific selectins, including SELL, SELE, and SELP. Endoglycan/PODXL2 Protein, Human (HEK293, His) is the recombinant human-derived Endoglycan/PODXL2 protein, expressed by HEK293 , with C-His labeled tag.

Human

Endoglycan/PODXL2 Protein functions as a ligand for vascular selectins, facilitating the rapid rolling of leukocytes over vascular surfaces by engaging in high-affinity divalent cation-dependent interactions with E-, P-, and L-selectins. It forms homodimers through disulfide linkages and interacts with specific selectin proteins, including SELL, SELE, and SELP. These interactions underscore its role in mediating crucial adhesive events that contribute to the intricate processes of leukocyte recruitment and vascular homeostasis.

Endoglycan; PODLX2; brain-1; BRN1; EG; oct-8; OTF8; UNQ1861/PRO3742

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.