protein

PLAU/uPA Protein, Mouse (Biotinylated, HEK293, His-Avi)

HY-P78018

20 μg;50 μg

230;500 USD

PLAU/uPA Protein, Mouse (Biotinylated, HEK293, His-Avi)

proteins

HEK293

20 μg;50 μg

230;500 USD

PLAU or urokinase-type plasminogen activator (uPA) critically initiates fibrinolysis by cleaving plasminogen to form active plasmin.This enzymatic conversion is critical for regulating clot dissolution and tissue remodeling.PLAU/uPA Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived PLAU/uPA protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

Mouse

PLAU, also known as urokinase-type plasminogen activator (uPA), plays a crucial role in fibrinolysis by specifically cleaving the zymogen plasminogen to generate the active enzyme plasmin. This enzymatic conversion is a pivotal step in the regulation of blood clot dissolution and tissue remodeling. PLAU's ability to activate plasmin sets in motion a cascade of proteolytic events, contributing to the breakdown of fibrin clots and extracellular matrix components. This process is essential for various physiological functions, including wound healing, tissue repair, and the resolution of blood clots.

PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.