protein

Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His)

HY-P77973

50 μg

360 USD

Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His)

proteins

HEK293

50 μg

360 USD

Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This underscores the diverse and essential functions of Plasma kallikrein/KLKB1 in various physiological processes.Plasma kallikrein/KLKB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

The Plasma kallikrein/KLKB1 protein demonstrates enzymatic activity by selectively cleaving Lys-Arg and Arg-Ser bonds. Upon binding to a negatively charged surface, it initiates a reciprocal activation of factor XII. Additionally, the protein plays a crucial role in releasing bradykinin from HMW kininogen. Intriguingly, it is implicated in the renin-angiotensin system, potentially contributing to the conversion of prorenin into renin. This intricate interplay underscores the diverse and essential functions of the Plasma kallikrein/KLKB1 protein in various physiological processes.

Plasma kallikrein; PKK; KLK3; KLKB1; Fletcher factor; Kininogenin

Greater than 95% as determined by Tris-Bis PAGE.

Supplied as a 0.22 μm filtered solution of 20 mM NaAc, 150 mM NaCl, pH 5.0.

Shipping with dry ice