protein

KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi)

HY-P77970

20 μg;50 μg;100 μg

115;220;350 USD

KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi)

proteins

HEK293

20 μg;50 μg;100 μg

115;220;350 USD

KIR2DL2/CD158b1, found on NK cells, functions as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its key role is to inhibit NK cell activity, serving as a regulator to prevent cellular lysis. Interacting with specific HLA-C molecules, KIR2DL2/CD158b1 contributes to the delicate balance of inhibitory signals in the immune system, shaping the responsiveness of NK cells to potential targets. KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL2/CD158b1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is 224 a.a., with molecular weight of 45-50 kDa.

Human

KIR2DL2/CD158b1, located on natural killer (NK) cells, serves as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its primary function is to exert inhibitory effects on NK cell activity, acting as a regulator to prevent cellular lysis. Through specific interactions with distinct HLA-C molecules, KIR2DL2/CD158b1 contributes to the finely tuned balance of inhibitory signals within the immune system, influencing the responsiveness of NK cells to potential targets.

Killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; NKAT-6; p58 NK receptor CL-43; CD158b1; KIR2DL2; CD158B1; NKAT6

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.