protein

Fibulin-3 Protein, Mouse (HEK293, His)

HY-P77921

20 μg;50 μg

200;441 USD

Fibulin-3 Protein, Mouse (HEK293, His)

proteins

HEK293

20 μg;50 μg

200;441 USD

Fibulin-3 protein plays multiple roles, binding to EGFR to induce downstream signaling and affecting cell adhesion and migration. It may negatively regulate chondrocyte differentiation and affect glial cell function in the olfactory epithelium, including migration, differentiation, and support of neurite outgrowth. Fibulin-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Fibulin-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of Fibulin-3 Protein, Mouse (HEK293, His) is 476 a.a., with molecular weight of 60-80 kDa.

Mouse

The Fibulin-3 Protein exhibits a multifaceted role by binding to EGFR, the EGF receptor, leading to EGFR autophosphorylation and the subsequent activation of downstream signaling pathways. This interaction suggests its involvement in crucial cellular processes such as cell adhesion and migration. Additionally, Fibulin-3 may function as a negative regulator of chondrocyte differentiation and, in the olfactory epithelium, potentially regulates glial cell migration, differentiation, and the ability of glial cells to support neuronal neurite outgrowth. Furthermore, it interacts with ECM1 and TIMP3, indicating its participation in intricate molecular networks that contribute to various cellular functions.

EFEMP1; FBLN3; FBNL; DHRD; FBNLFLJ35535; FIBL-3; fibrillin-like; Fibulin 3; MGC111353; MLVT; MTLV; S1-5

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.