protein

DSG2/Desmoglein-2 Protein, Mouse (HEK293, His)

HY-P77918

20 μg;50 μg;100 μg

230;440;700 USD

DSG2/Desmoglein-2 Protein, Mouse (HEK293, His)

proteins

HEK293

20 μg;50 μg;100 μg

230;440;700 USD

DSG2/Desmoglein-2 proteins mediate cell-cell adhesion by interacting with plaque proteins and intermediate filaments at desmosome junctions. It plays a vital role in desmosome structure, maintaining tissue integrity and cohesion. DSG2/Desmoglein-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DSG2/Desmoglein-2 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

DSG-2, a key constituent of intercellular desmosome junctions, plays a pivotal role in mediating cell-cell adhesion by participating in the interaction between plaque proteins and intermediate filaments. This integral involvement in desmosomal structures underscores its significance in maintaining tissue integrity and cohesion. Notably, DSG-2 forms essential connections within the desmosome complex, contributing to the robustness of intercellular adhesion. Furthermore, its interaction with PKP2 further emphasizes the intricate molecular network that orchestrates the stability and functionality of desmosomes in cellular junctions.

Desmoglein-2; HDGC; DSG2; CDHF5; ARVC10; CMD1BB; MGC117036; MGC117037

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.