protein

CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc)

HY-P77906

20 μg;50 μg;100 μg

125;250;400 USD

CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc)

proteins

HEK293

20 μg;50 μg;100 μg

125;250;400 USD

CLEC5A/MDL-1 Protein positively regulates osteoclastogenesis and acts as a cell surface receptor signaling via TYROBP. Its expression relies on the TYROBP interaction and it plays a role in regulating inflammatory responses. CLEC5A/TYROBP/HCST complex formation highlights its intricate involvement in immune and inflammatory processes. CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-hFc labeled tag.

Mouse

CLEC5A/MDL-1 Protein acts as a positive regulator of osteoclastogenesis and functions as a cell surface receptor that signals via TYROBP. This interaction is vital for CLEC5A cell surface expression. Additionally, the protein plays a role in regulating inflammatory responses. While existing as a monomer or homodimer, the majority of CLEC5A is expressed as a monomeric form on macrophages. It forms a trimolecular complex, CLEC5A/TYROBP/HCST, mainly dependent on TYROBP. The interaction with TYROBP and HCST further underscores the intricate signaling network involved in the functions of CLEC5A in immune and inflammatory processes.

MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.