protein

ADAM9 Protein, Human (HEK293, His, solution)

HY-P77867

20 μg;50 μg;100 μg

185;350;560 USD

ADAM9 Protein, Human (HEK293, His, solution)

proteins

HEK293

20 μg;50 μg;100 μg

185;350;560 USD

ADAM9, a metalloprotease, cleaves and releases TEK, KDR, EPHB4, CD40, VCAM1, and CDH5, playing a pivotal role in tumorigenesis and angiogenesis. It regulates cell motility through integrin interactions, mediates cell-cell and cell-matrix interactions, and may act as an alpha-secretase for APP, suggesting involvement in neurobiology and neurodegenerative disorders. ADAM9 Protein, Human (HEK293, His, solution) is the recombinant human-derived ADAM9 protein, expressed by HEK293 , with C-His labeled tag. The total length of ADAM9 Protein, Human (HEK293, His, solution) is 669 a.a., with molecular weight of 40-45 kDa.

Human

ADAM9, a metalloprotease, plays a pivotal role in tumorigenesis and angiogenesis by cleaving and releasing various molecules including TEK, KDR, EPHB4, CD40, VCAM1, and CDH5. Its multifaceted functions extend to mediating cell-cell and cell-matrix interactions, thereby regulating cell motility through interactions with integrins. Additionally, ADAM9 may function as an alpha-secretase for the amyloid precursor protein (APP), highlighting its involvement in processes relevant to neurobiology and neurodegenerative disorders.

ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG

Greater than 95% as determined by Tris-Bis PAGE.

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, 500 mM NaCl, 0.005% Brij-35,20% Glycerol (pH8.5).

Shipping with dry ice