protein

Nectin-3/CD113 Protein, Human (309a.a, HEK293, His)

HY-P7782

10 μg;50 μg

95;285 USD

Nectin-3/CD113 Protein, Human (309a.a, HEK293, His)

proteins

HEK293

10 μg;50 μg

95;285 USD

CD113 Protein, Human (HEK293, His) is a recombinant human CD113 expressed in HEK 293 cells with a His tag at the N-terminus. CD113 Protein is a member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities [1] [2] .

Human

Nectin is a Ca 2+ -independent immunoglobulin-like intercellular adhesion molecule. Nectin comprises a family of at least four members nectin-1, nectin-2, nectin-3 and nectin-4. All the members have two or three splice variants (except nectin-4), and have an extracellular region containing three Ig-like domains, a single transmembrane region and a cytoplasmic region (except nectin-1γ). Nectin-1, nectin-2 and nectin-3 are ubiquitously expressed in a variety of cells. Nectin-2 and nectin-3 are also expressed in cells that lack cadherins. Nectin-4 is expressed mainly in the placenta. Nectin-3 has three splicing variants, nectin-3α (biggest), -3β (middle), and -3γ (smallest). Nectin-3α consists of three extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic region with the C-terminal consensus motif for binding to the PDZ domain [1] [2] .

rHuCD113, His; Poliovirus Receptor-Related Protein 3; CDw113; Nectin-3; CD113; PVRL3; PRR3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 5% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.