protein

VCAM-1/CD106 Protein, Human (HEK293, His)

HY-P7777

10 μg;50 μg

65;195 USD

VCAM-1/CD106 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

65;195 USD

CD106 Protein, Human (HEK293, His) is a cytokine-inducible cell surface protein capable of mediating adhesion.

Human

CD106 (VCAM1) serves as a ligand for very late antigen-4 (VLA-4), which is present on leukocytes. CD106 (VCAM1) is a component of the neural stem cell niche that is critical for MSC-mediated immunosuppression and hematopoietic progenitor cell binding. CD106 promotes strong adhesion of leukocytes to the endothelium. Cell-to-cell adhesion mediated by CD106 is known to be critical for T-cell activation and leukocyte recruitment to inflammatory sites, and therefore it plays an important role in evoking effective immune responses. CD106 is highly expressed on chorionic villi (CV)-MSCs, moderately expressed on BM-MSCs, poorly expressed on umbilical cord MSCs, and not expressed on adipose MSCs [1] .

rHuCD106, His; Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; VCAM1; L1CAM

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 2 mM CaCl 2 , 2 mM MgCl 2 , 5% Threhalose, pH 7.2.

Room temperature in continental US; may vary elsewhere.